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They were reconstructed following the producers directions

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Activation of Y1R results in osteoclast formation, negatively impacting bone maintenance, while activation of Y2R influences bone remodeling by modulating the activity of the sympathetic nervous system

Yet, the expression of this transporter in different parts of the gut (Figure 2B) does not exclude its possible participation in the guts absorption of ThDP from the diet, especially given the presence of other folate transporters on the brush border membrane of enterocytes, i.e., those encoded by SLC46A1, FOLR1, and FOLR2 (119)

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