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93 (Suppl 1), S157S161 (2005)

If you have been instructed to follow a low protein diet, consult a healthcare practitioner prior to use

Patient reported having bowel movements and no further nausea or vomiting

Slow dose escalation mitigates these effects substantially, and discontinuation due to gastrointestinal intolerance ranges from 3% to 16% across agents, being highest for GLP-1/glucagon dual agonists (e.g., survodutide)