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Metrnl alleviates lipid accumulation by modulating mitochondrial homeostasis in diabetic nephropathy

Concomitant therapy with metformin, incretins, and SGLT2 inhibitors should be continued with regimens containing bolus insulin to support glycemic management with less risk of weight gain and hypoglycemia [75,76,81-102]

Who it tends to work well for: Patients who want a more aggressive approach or who havent responded as well to GLP-1-only treatments

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