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10.1007/s12094-018-1833-4 98

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Thus, modulation of GSH levels could be proposed as a therapeutic target in HTLV-1-associated diseases

Furthermore, the main known mechanisms of metformin in regulating the glioma signaling pathway include regulating oxidative stress, modulating glioma immunity, activating the AMPK signaling pathway, inhibiting the mTOR signaling pathway, suppressing the nuclear abundance of YAP, and interfering with the activity of intracellular chloride channels