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This mechanism provides a valuable research model for investigating aging biology, cell-cycle regulation, and the role of senescent cells in tissue function

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[4] The result is a GHRH-receptor agonist that survives slightly longer in circulation than the unmodified hormone while still producing the same fundamental action: stimulation of the somatotroph cells of the anterior pituitary to release GH in a pulsatile, physiologic pattern, which in turn raises IGF-1