The two short-acting GLP-1 RAs, exenatide BID and lixisenatide, both caused a maximum HR increase of 810 bpm 24 h after injection, which returned to baseline levels after approximately 1012 h (Sanofi, data on file [available on request [22] ] and [19, 20]), with a mean 24-h HR increase of approximately 12 bpm for both preparations
Back Marks, V (Feb 2018) 'Rebirth of the Incretin Concept: Its conception and early development', Peptides , 100, 3-9
Liraglutide repairs the infarcted heart: The role of the SIRT1/Parkin/mitophagy pathway
The STEP (Semaglutide Treatment Effect in People with obesity) clinical trial program, which evaluated once-weekly semaglutide 2.4 mg for weight management, demonstrated significant weight loss (approximately 15% in STEP 1) that could indirectly affect hormone levels, though testosterone was not systematically reported in these publications
This isnt required, but it can smooth the screening process