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Fertility Medications Concern: Melatonin is a hormone that could theoretically affect reproductive hormones

Normalization of high baseline ALT was seen at week 52 in 29% (17/58

ICI-induced colitis differs from inflammatory bowel disease (IBD) because is usually reversible ( Long-Term Adverse Effects of ICIs ICIs have been successfully introduced in the treatment of various cancers only a few years ago

The same review in Children noted that major gaps remain in the data, including a lack of long-term safety and growth information, limited pediatric-specific dosing research, and open questions about how these medications interact with puberty over time

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