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Ethics statement The institutional review board of Chonnam National University Hospital approved the study protocol (CNUH-EXP-2021-431)

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Contraindications History of cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension) During or within 14 days following the administration of monoamine oxidase inhibitors Hyperthyroidism Glaucoma Agitated states History of drug abuse Pregnancy [see Use in Specific Populations (8.1)] Nursing [see Use in Specific Populations (8.3)] Known hypersensitivity, or idiosyncrasy to the sympathomimetic amines 5