Both medications can significantly reduce hunger and food intake
The hallmark symptom of acute pancreatitis is severe, persistent abdominal pain , typically located in the upper abdomen (epigastric region) and often described as: Sudden onset and constant (not cramping or intermittent) Severe intensity that may worsen after eating Radiating through to the back or between the shoulder blades Accompanied by a tender abdomen when touched Associated symptoms that frequently occur alongside the abdominal pain include: Nausea and persistent vomiting Fever and rapid pulse Abdominal swelling or distension Loss of appetite Feeling generally unwell (malaise) It is crucial to distinguish pancreatitis symptoms from the common gastrointestinal side effects of GLP-1 agonists, which affect a significant proportion of users, particularly during treatment initiation
doi:10.1038/s41419-019-1706-y Araj-Khodaei M, Ayati MH, Azizi Zeinalhajlou A, et al
Mitochondrial fission is associated with apoptosis (51), and increased fission can lead to mitochondrial fragmentation, reduced membrane potential, and decreased ATP production
Most patients need to continue treatment indefinitely to maintain weight loss
