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In the STEP 4 clinical trial, semaglutide users who stopped using the medication regained 6.9% of their body weight after 48 weeks

This review examines the main effects of GLP-1 and its analogs, GLP-1RA, on the body, with a focus on the brain mechanisms mediated by the GLP-1R, which form the basis for using these compounds to treat brain diseases and comorbidities

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Hayes JD, Pulford DJ (1995) The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance