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It has been reported that there is a strong positive correlation between postprandial total BAs and FGF19, possibly because BAs bind to FXR and stimulate FGF19 synthesis [100]

Signs that you need more than fiber If you have been taking an appropriate fiber supplement at full dose with adequate hydration for 2 or more weeks and you are still experiencing fewer than 3 bowel movements per week, straining with most bowel movements, hard or lumpy stool consistently, or abdominal pain associated with constipation, fiber alone is not going to solve the problem

The most common side effects are gastrointestinal: nausea, stomach discomfort, bloating, or changes in bowel habits

Also, it will have an impact on the broader ecosystem of healthcare services, potentially changing your patients population characteristics and their journey

[DOI] [PubMed] [Google Scholar] 66.Blundell J., Finlayson G., Axelsen M., Flint A., Gibbons C., Kvist T