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"In addition to the surveillance previously recommended for the potential association of GLP-1 based therapy and pancreatic cancer risk, the current data imply that surveillance for a possible increased risk of pancreatic neuroendocrine tumors is warranted." Such surveillance approaches might include MRI imaging of the pancreas and screening for neuroendocrine tumors, Butler said

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The company also noted that the rate of elevated liver enzymes in people who have taken danuglipron is in line with approved GLP-1 drugs, which is based on a safety database of more than 1,400 patients who have taken Pfizer's pill

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However, several over-the-counter dietary and herbal products, marketed to support thyroid health and to lose weight, contain excessively high amounts of iodine, sometimes above the TUL, and their use should be discouraged, according to the ATA recommendations [22, 34, 52]

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