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Many people ask about the best time of day to take it

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Your prescriber may recommend slowing your dose escalation, temporarily reducing your current dose, or switching to a different formulation (oral versus injection, for example) if vomiting is intractable

Roelofzen JH, Aben KK, Oldenhof UT, Coenraads PJ, Alkemade HA, van de Kerkhof PC,

Muscle loss and gallbladder problems are known to occur in folks taking GLP-1 receptor agonists, though these issues tend to result from rapid weight loss more generally