Weller et al., 1998
This makes glutathione a crucial player in the fight against oxidative stress and cellular damage
Unfortunately, the human digestive system is very good at breaking down proteins
However, in resistant patients, oxidative stress causes a conformational change in Keap1, leading to the release of NRF2, which translocates to the nucleus and binds to antioxidant response element (ARE), activating the expression of downstream antioxidant genes, including GPX4, NQO1, HO-1 and SOD1 [33], and promoting the synthesis of GSH, as illustrated in Fig
Unlike standard antioxidant tests that only assess total levels, this test evaluates both reduced glutathione (GSH) and oxidised glutathione (GSSG) to calculate your GSH:GSSG ratio, a gold-standard biomarker of oxidative stress and redox balance