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Therefore, the acidic residues of p53 TAD appear to have no significant impact on its interaction with the FOXO4 FHD, as these residues primarily contribute to DNA selectivity rather than binding to the FOXO4 FHD

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In weight management, semaglutide works not only by controlling blood sugar but also by reducing appetite, which leads to eating fewer calories overall

IRB and IACUC Protocols: Researchers conducting animal model studies with peptides are required to obtain appropriate Institutional Review Board (IRB) or Institutional Animal Care and Use Committee (IACUC) approvals

For peripheral nerve analysis, a 5-mm-long piece of tail 15 mm distal from the tail base was collected from each sacrificed animal, fixed in 4% formaldehyde in phosphate buffer (pH 7.4), decalcinated, and impregnated with 1% osmium tetroxide for a few days