For directed pathway graphs, there are two types of degrees: in-degree for links came from other nodes, and out-degree for links initiated from the current node
and the biological pathways in which differential genes were involved included apoptotic process involved in development, extracellular structure organization, activation of MAPKK activity, apoptotic process involved in morphogenesis, positive regulation of coagulation, positive regulation of hemostasis, positive regulation of blood coagulation, regulation of apoptotic process involved in development, cell junction maintenance, and regulation of apoptotic process involved in morphogenesis
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In addition, the patients was further divided into 4 groups according to the total motile sperm count based on the WHO reference as less than 0.510 6
Oxidative stress in diabetic peripheral neuropathy: pathway and mechanism-based treatment