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[DOI] [PubMed] [Google Scholar] 48.Marx N, et al

Lixisenatide: evidence for its potential use in the treatment of type 2 diabetes

BNIP3 interacting with LC3 triggers excessive mitophagy in delayed neuronal death in stroke

Over a 36-month period, the incidence of NAION in semaglutide users was 8.9%, compared to just 1.8% in the non-GLP-1 RA cohort

The increase in risk was small approximately three to four additional cases per 10,000 patients treated with GLP-1s over 18 months, but clinicians and patients should be aware of this potential association. Researchers said while the risk is low, the rising use of GLP-1s in patients with and without Type 2 diabetes warrants special attention to medication safety