Participants also showed improvements in several metabolic parameters, including fasting glucose, insulin sensitivity, lipid profile, and blood pressure
Common side effects may include temporary flushing, nausea, or headache
It is, therefore, reasonable to consider that the postprandial rise in GLP-1 might affect feeding behavior after RYGB, and to a lesser extent SG, where the increase in GLP-1 is less marked (72) have shown that inhibition of GLP-1 actions in the postprandial period has limited effects on glucose concentrations in people after RYGB
Dulaglutide (Trulicity) Strengths: Once-weekly dosing Easy-to-use auto-injector device Proven cardiovascular benefit Good tolerability profile Considerations: Less weight loss than semaglutide Moderate (not maximum) glucose efficacy Best for: Patients prioritizing convenience and tolerability over maximum efficacy
These changes are relatively small and suggest that the GSH/GSSG pool within the cells is tightly regulated