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Mojca Jensterle provides additional perspective, stating: The use of GLP-1RAs in PCOS is currently not widely accepted and recognized by clinicians

Early clinical evidence backs this, showing a significant number of participants shedding a substantial amount of weight and other health indicators improving

The dosing approach typically follows an escalation protocol to minimize gastrointestinal side effects while achieving optimal receptor activation: The cagrilintide starting dose of 0.6 mg allows the body to adapt to amylin receptor activation gradually

These therapies hold promise as nonspecific immunomodulators, offering new approaches to regulating gut microbiota composition and potentially predicting patient responses to treatment