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3 The pathogenesis of AKI The primary factors leading to AKI encompass sepsis, nephrotoxic agents, renal I/R injury, rhabdomyolysis (RM), post-major surgeries, etc (Tang C

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Perhaps blocking H4R may limit neutrophil invasion and put the brakes on perpetuating this cycle with a shut-off signal at the innate immune level, and this may be most successful in a specific set of patients that retain a fully functioning adaptive immune system

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Folic acid may be a cofactor in phenytoin metabolism