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The appetite-suppressing effect in the brain appears more durable than the stomach-slowing effect, but the early, very palpable sense that food simply isnt interesting does tend to soften over time

The more muscle you have, the more calories your body burns even at rest

lfod14 2024-08-22 21:01:01 UTC #6 From playing with the dosages a lot over the last year or two, seems the 0.25mg is pretty much the lowest dose where you can actually notice it working, you can adapt pretty quickly, especially if you follow the dosage guidelines, but for appetite suppression, you definitely dont need to ramp the dose up like youre supposed to, for a while when I upd to 0.25mg/2xwk which kept the suppression down better after I originally adapted

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You can read that here.