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The eukaryotic extracellular SOD Cu-Zn SOD is encoded by the SOD3 gene mapping to chromosome 4.27 Substantial amount of SOD3 is found virtually in all human tissues

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Therefore, we examined the behavior of adult, control and DG-NR1KO mice ( n = 22 and 21 mice, respectively) in the novelty-suppressed feeding test, open field test and elevated plus maze (Santarelli et al., 2003