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They provide the most benefit when combined with a healthy diet and regular physical activity

Day 1: 100-200 mg NAD IV (1-3 hrs) Day 4: 50mg NAD SQ Day 6: 50mg NAD SQ Daily: 250mg NR/NMN in the morning Week 3 We also keep roughly the same routine, though you can ramp up to 500mg NAD IV at this point if you feel you can tolerate it's side effects during infusion

And its even worse for people who dont inject on a daily basis: Vitamin B12 is water-soluble, so only a tiny bit is absorbed, and the rest is urinated out within hours

Supplementation of some vitamins at higher doses level can cause toxicity