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At the same time, it preserved the homeostasis of CD8+ splenocytes, maintaining their cytotoxic function without provoking an excessive inflammatory response [50], suggesting Epitalons role in recalibrating, rather than overactivating, immune function

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Importantly, concentrations of GLP-1 936 amide (1 M) and compound 2 (10 M) that evoked little or no increase in [Ca 2+ ] i alone (thapsigargin-sensitive increase in fluorescence) produced a marked increase when added in combination (Figure 6E) indicating that compound 2 potentiates Ca 2+ signaling by GLP-1 936 amide

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