sglt2 inhibitors vs glp 1 Perspectives in weight control in diabetes – and GLP-1–glucagon dual agonism Use of GLP-1 Receptor Agonists

Risk factors for HFpEF include obesity and type 2 diabetes

[16] Reported rates from trials include: Nausea: ~44% Vomiting: ~25% Diarrhea: ~31% Constipation: ~23% Dyspepsia: ~10% These effects reflect slowed gastric motility and are usually mild, but can lead to clinical implications: Dehydration Electrolyte abnormalities ED presentations for poor oral intake

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In addition to secreted ATP from type II cells, type III cells get depolarized in response to acids [41]