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FDA approval Phase 1, 2 and 3 clinical trials require companies to perform extensive clinical studies to determine drug safety and efficacy

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Notably, LCA has been found to activate Taste Receptor Type 2 Member 1 (TAS2R1) in humans at a concentration of 0.3 M, while TLCA activates TAS2R1, TAS2R14, and TAS2R46 at the same concentration

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Physiol Behav 2012;105:772-776

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Nothing made much of a difference

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