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Consistent with these findings, semaglutide upregulates key -oxidation regulators (e.g., peroxisome proliferator-activated receptor (PPAR), carnitine palmitoyltransferase 1A (CPT1A), peroxisome proliferator-activated receptor-gamma co-activator 1- (PGC-1) in adipose and liver of obese mice [38,41]