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The SGLT2i rely on adequate glomerular filtration for their glycaemic benefit and are not as effective at glycaemic control in patients with CKD

Access and affordability are significant challenges, as are governmental policies, such as the current prohibition on Medicare coverage for weight loss medications in the US, restrict availability for many individuals who could benefit from these therapies

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Side Effects While generally well-tolerated, Testosterone Enanthate can be associated with side effects

Ozempic uses multi-dose pens that contain several weeks worth of medication with adjustable dosing