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pharmacovigilance study analyzing 15,597 tirzepatide reports found no significant signals for depression or suicidality and a mortality rate of just 0.26% , lower than other anti-obesity medications

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We then examined the expression levels of hypoxia modulator HIF-1, apoptosis marker caspase 3, and lipid droplet marker PLIN2 in PASMCs treated with neohesperidin and naringin