This FDA-approved medication works by regulating appetite, reducing cravings, and improving how your body manages energy, making it a powerful option for those looking to lose weight effectively
Understanding where and how GLP-1 is produced provides insight into both normal metabolic function and the rationale behind GLP-1-based medications
By targeting glucagon, retatrutide may help the body access and use stored energy more efficiently, while the targeted GLP-1 and GIP hormones help support fullness, appetite control, and blood sugar regulation
Dehydration represents an important factor, as GLP-1 medications can cause nausea, vomiting, and diarrhea, particularly during dose escalation, leading to volume depletion
doi: 10.1001/jama.2024.2252