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and it is noticeable
While tirzepatide is not primarily eliminated through the kidneys, the gastrointestinal effects of the medication, including potential nausea, vomiting, and diarrhea, could lead to dehydration and electrolyte imbalances that may be particularly problematic in patients with compromised kidney function
The landmark SURMOUNT-OSA trial found that tirzepatide reduced the apnea-hypopnea index (AHI), the standard measure of sleep apnea severity, by approximately 50 to 60 percent at 52 weeks (Malhotra et al., New England Journal of Medicine , 2024)
A maintenance dose is the dose given regularly over the long term to maintain the desired effect after the initial response has been achieved
1,6,9 Some adolescents may try to self-medicate for nausea with marijuana, but this can actually worsen CVS
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