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Analogs such as GS-445124 have been found to act as an RNA-chain terminator and an alternative substrate of viral RNA dependent RNA polymerase

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This proportion of super responders people that lose at least 20 percent of their starting weight is similar to whats seen when people take injected GLP-1 medications, says Jody Dushay, MD, an endocrinologist at Beth Israel Deaconess Medical Center and an assistant professor at Harvard Medical School in Boston

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