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The gene spans 18 kb and is composed of 14 exons that generate three alternatively spliced mRNAs

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Life Sci 267:118954 Furino VDO, Alves JM, Marine DA, Sene-Fiorese M, Rodrigues CNDS, Arrais-Lima C, Mattiello SM, Castro CAD, Borra RC, Rocha MC, Malavazi I, Duarte ACGDO (2021) Dietary intervention, when not associated with exercise, upregulates irisin/FNDC5 while reducing visceral adiposity markers in obese rats

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