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Pro-inflammatory chemicals such as cytokines (IL-1, IL-6, TNF), adhesion molecules (ICAM-1, VCAM-1), matrix metalloproteinases (MMPs) and prostaglandins are quickly activated [25]

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GLP-1 users are buying less, but trading up: spending is shifting toward fewer, higher-quality, and often more expensive items, which means the opportunity for premium positioning is real even in categories facing headwinds on pure volume