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They affect appetite and metabolism but are not addictive substances

Within the tumor microenvironment (TME), lipid peroxidation is regulated by various factors in addition to fatty acids, such as reactive oxygen species (ROS), iron, and glutathione (GSH) [55] E.g., tumor growth requires substantial energy consumption and simultaneously generates elevated levels of ROS [56]

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Data in panel h , i comprise n = 8 for WT-Vhcl, WT-GLP-1:GIP, GIPRtg-Vhcl and GIPRtg-GLP-1:GIP:Lani, n = 7 for WT-GLP-1:GIP:Lani and n = 6 for GIPRtg-GLP-1:GIP

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