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Look for the leading indicators: changes in appetite, satiety signals, and subject feedback

Participants receiving 8 mg weekly achieved around 17% weight loss over 36 weeks, with weight continuing to fall when follow-up was extended

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Importantly, endogenous GSH production begins to decline after age thirty, increasing vulnerability to environmental insults and chronic disease

10.1517/13543784.2014.892582 111 LiuT.YangQ.ZhangX.QinR.ShanW.ZhangH.et al (2020)