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341 For instance, treatment with nerve growth factor (NGF) or brain-derived neurotrophic factor (BDNF) enhances neurite outgrowth and supports neuronal survival

Rats undergoing surgical connection of the esophagus to stomach exhibited severe complications without treatment

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Akkermansia muciniphila comprises 3%5% of mouse gut microbiota but only 1%3% in humans ( 3.1.4.3 Strategies to bridge translational difficulties To improve clinical translatability, the following strategies are recommended: (1) Multi-species validation: mechanisms discovered in mice should be validated in rats, rabbits, or non-human primates