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Nat Med (2006) 12:106574

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Acetyl-L-carnitine is better absorbed and crosses the blood-brain barrier more rapidly than L-carnitine.* Studies have demonstrated its effectiveness in supporting cognitive health and maintaining a positive mood in the elderly, possibly by partially inhibiting the activity of the hypothalamic-pituitary-adrenal axis and lowering chronically elevated cortisol levels, which become elevated during stress.* In addition to acetyl-L-carnitine's support of brain and nerve health, it also promotes healthy sperm count and motility