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According to the Missouri Poison Center, signs of a semaglutide overdose include: Feeling lightheaded or dizzyFeeling shaky or jitterySweating, chills and clamminessIrritability or impatienceHeadacheWeaknessFatigueNausea and/or vomitingSeizuresConfusionPassing out If you think you have overdosed on a weight loss drug, Brown said the best thing to do is call your local poison control center or the national hotline at 800-222-1222

Your appetite wont be reduced as much as it was when you were on the medications, but some evidence-based strategies can reduce it

Effects gradually diminish as levels drop over this period