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The caprylate/chromatography manufacturing process was also investigated for its capacity to decrease the infectivity of an experimental agent of transmissible spongiform encephalopathy (TSE), considered as a model for the variant Creutzfeldt-Jakob disease (vCJD), and Creutzfeldt-Jakob disease (CJD) agents.(1) These studies provide reasonable assurance that low levels of vCJD/CJD agent infectivity, if present in the starting material, would be removed by the caprylate/chromatography manufacturing process

Alzheimers disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

Faced with the stubborn drug resistance of flucytosine, researchers began to take a fresh look at drugs targeting fungal DNA synthesis and developed the corresponding nano-agents against Candida albicans

QZ: Methodology, Writing review and editing

PMID 24142589