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Understanding and Easing Herxheimer Reactions During Lyme Treatment By Jenny Lelwica Buttaccio If youve had Lyme disease for a while, youve probably heard some challenging stories about the dreaded Herxheimer reaction. For some Lyme patients, the thought of having to endure an uncomfortable reaction on top of already debilitating Lyme symptoms is too much to bear

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Over time or in high doses, [the effects] can escalate to severe liver inflammation and an increased risk of acute liver failure

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Side effects that persist or worsen may indicate that a different medication or a different approach is more appropriate