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Given that both of these studies were in patients with OA of the knee (a load-bearing joint), it is likely that a significant proportion of the efficacy observed was due to the significant loss of body weight, reducing pathological joint loading

W., Elsaesser, S

Three to four protein-containing meals and snacks per day is better than one massive protein meal

Most attention has focused on the ascorbate-glutathione pathway, but several other candidate pathways may couple the availability of oxidants such as H 2 O 2 to changes in glutathione and thus impact on signaling pathways through regulation of protein thiol-disulfide status

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