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In the SUSTAIN 6 trial, over 3,297 patients with type 2 diabetes with established chronic kidney disease and/or cardiovascular disease underwent randomization to semaglutide or placebo and were followed for 2 years resulting in a 26% risk reduction in the combined endpoint of rate of cardiovascular disease, nonfatal myocardial infarction, or nonfatal stroke [47]

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In the case of illness or injury, the person's skin may change color, becoming darker (hyperpigmentation) or lighter (hypopigmentation)

Johnstone AM, Murison SD, Duncan JS, Rance KA, Speakman JR: Factors influencing variation in basal metabolic rate include fat-free mass, fat mass, age, and circulating thyroxine but not sex, circulating leptin, or triiodothyronine

In parallel, further research on the potential role of ferroptosis in chronic infections may provide new insights for developing effective treatment strategies