Other Reasons GLP-1s Might Make You Feel Cold Beyond brown fat and BMR changes, there are a few more subtle (and often overlooked) reasons why GLP-1 meds can leave you reaching for a hoodie in summer: Muscle loss : Muscle mass helps generate heat
Cocaine and amphetamines (stimulants) All animal studies retrieved for stimulants misuse involved exendin-4 among GLP-1RAs and highlighted a reduction of cocaine and amphetamines intake and end effects (for example, increased locomotor activity) via modulation of dopaminergic transmission in areas including the nucleus accumbens and the ventral tegmental area 91,92,93,94,96,97,98,99,100,101,102,103,105 , as well as modulation of inflammatory mechanisms 104
Effects of glucagon, catecholamines, and adenosine 3,5-monophosphate on gluconeogenesis in the perfused rat liver
In some cases, GLP-1s might help people get pregnant, but once someone is expecting, its a different story
Skin Sensitivity and Preparation Problems Preparing your skin properly is key to minimizing irritation
