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Because the core mechanism papers were retracted, even the premise that Dihexa potently engages HGF/c-Met in a living human brain at community-reported doses is not established fact

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"Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin." Disease Management & Clinical Outcomes , 1998

Hematologic changes and serum B12 rise over weeks to months