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Kannt A, Pfenninger A, Teichert L, Tnjes A, Dietrich A, Schn MR, Klting N, Blher M. Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance. Diabetologia. 2015 Apr;58(4):799-808. doi: 10.1007/s00125-014-3490-7. Epub 2015 Jan 18. PMID: 25596852; PMCID: PMC4351435

Daily basics: Water first: start your day with a full glass Fiber from food: beans, lentils, oats (if you like), berries, chia Movement: even a 10-minute walk after meals helps Travel hack: pack what works for you (fiber supplement you tolerate, stool softener if your clinician approves, electrolyte packets, etc.)

Scenario 2: Man on TRT adding GLP-1 You are 45, on testosterone replacement therapy for diagnosed hypogonadism, and carrying 50 excess pounds of primarily visceral fat

Recovery timelines vary widely

Abenavoli L, Scarlata GGM, Paravati MR, Boccuto L., Luzza F., Scarpellini E