GSH depletion is strongly associated with impaired immune function and with disease development including viral diseases, cancer, cardiovascular diseases, arthritis and diabetes (Sinha et al., 2018
J Allergy Clin Immunol 120 : S94S138 Wenzel SE, Fahy JV, Irvin C, Peters SP, Spector S, Szefler SJ, for the American Thoracic Society Workshop 2000 Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions
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To date, although findings advised that G6PD deficiency may lessen free radicals production in failing myocardium and may decrease the risk of coronary heart disease progression, an increase in oxidative stress along with heart failure is also observed in G6PD deficient failing myocardium [206]
However, regarding the overall bacterial composition, H
