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However, the therapeutic utility of doxorubicin is undermined by its dose-dependent cardiotoxicity, possibly arising as a result of futile redox cycling, with NADH dehydrogenase within the mitochondria proposed as the most likely site of anthracycline reduction 9,10

Generally administered into areas like the abdomen or upper arm, it's key that dosages are managed with healthcare supervision to ensure optimal treatment outcomes

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doi:10.3390/ijms21176190 4.Pickart L, Vasquez-Soltero JM, Margolina A

then a 20 mg/kg dose (the typical therapeutic dose) produces a gut concentration of 6000 M, assuming 75% bioavailability