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The primary efficacy endpoint assessed by the research team was the change from baseline in HbA1c levels following the 12 week experimental treatment period

Even with the caveats and asterisks on berberines benefits, they do exist and can be helpful to some, particularly for: people who are dealing with insulin resistance or metabolic syndrome those aiming for modest weight losstypically in the range of 10 to 15 pounds people who are looking for extra support in maintaining healthy blood sugar levels If you fall into any of these groups, berberine may support your metabolic health and weight management efforts

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It is approved only for type 2 diabetes management, and whilst modest cholesterol improvements have been observed in trials, these are secondary effects rather than primary therapeutic outcomes