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doi: 10.1016/j.yexcr.2024.114077 127 ContrerasHRLedezmaRAVergaraJCifuentesFBarraCCabelloPet al

The mechanisms proposed have included effects on growth factor activity, on extracellular matrix remodeling in the follicle environment, and on copper-dependent enzymes relevant to follicle biology

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Of these 50 semaglutide-treated patients that developed anti-semaglutide antibodies, 28 patients (1.6% of the overall population) developed antibodies cross-reacting with native GLP-1.The in vitro neutralizing activity of the antibodies is uncertain at this time